PRX⁸ Plant-Exo Stimulation System
PRX⁸ Plant-Exo Stimulation System
Description
PRX⁸ Plant-Exo Stimulation Serum
Professional Plant-Exo Stimulation Serum
PRX⁸ is a professional-use renewal serum designed to support
skin renewal, collagen-focused protocols, visible tone and texture improvement, and advanced microneedling outcomes.
Built to begin in the treatment room and continue at home when directed by a provider, PRX⁸ creates a more continuous approach to aesthetic treatment.
At the center of the formula is the PRX⁸ Complex™, supported by
ultracentrifuge-extracted Plant Exosomes, Copper Tripeptides, and micro-encapsulated 0.5% All-Trans Retinol.
Together, these ingredients support cellular communication, collagen signaling, visible renewal, hydration, and progressive skin refinement.
PRX⁸ has also been incorporated into clinical case work combining topical plant-derived exosomes with Collagen P.I.N. microneedling for concerns including
melasma and nonscarring alopecia, expanding its role beyond traditional facial rejuvenation protocols.
Professional protocol fit
One stimulation serum. Multiple treatment objectives.
- Signs of aging
- Skin quality
- Uneven tone
- Melasma-focused protocols
- Texture irregularity
- Collagen stimulation
- Hair restoration protocols
- Androgenetic alopecia
- Traction alopecia
- Post-treatment continuation
What it does
Extends stimulation beyond the microneedling treatment itself.
- Supports conditions for cellular turnover and collagen stimulation
- Pairs professional microneedling with targeted plant-exosome support
- Helps improve the appearance of uneven tone, dullness, and rough texture
- Supports visible renewal with micro-encapsulated All-Trans Retinol
- Provides Copper Tripeptide support for collagen-focused protocols
- Supports advanced scalp and hair-restoration protocols
- Creates continuity between in-office treatment and provider-directed home care
- Provides lightweight hydration and supportive barrier care during renewal
Why PRX⁸ is different
More than recovery. Designed to keep the treatment moving forward.
Many post-treatment serums are designed primarily to soothe and hydrate. PRX⁸ takes a different approach. It combines Plant Exosomes, Copper Tripeptides, All-Trans Retinol, and supportive ingredients to reinforce the biological environment surrounding renewal and collagen-focused treatment.
That makes PRX⁸ particularly useful in provider-led protocols where the goal extends beyond immediate post-procedure comfort—from visible skin rejuvenation and pigment-focused treatment to scalp stimulation and hair-restoration programs.
Clinical + provider results
PRX⁸ Across Different Treatment Concerns
Scroll through results from Collagen P.I.N. + PRX⁸ protocols spanning facial rejuvenation, hair restoration, and pigment-focused treatment.
Visible Aging + Skin Quality
Collagen P.I.N. microneedling paired with PRX⁸ as part of a collagen-focused rejuvenation protocol designed to support smoother texture, visible renewal, and overall skin quality.
Collagen P.I.N. • 0.5 mm
Androgenetic Alopecia
In a clinical case series co-authored by Dr. Shino Bay Aguilera, a male patient with androgenetic alopecia underwent three monthly scalp microneedling treatments with topical PRX⁸ plus provider-directed home use. Physician assessment reported increased hair density, growth, and scalp coverage.
Collagen P.I.N. • 0.5 mm • 3 Monthly Treatments
Traction Alopecia
The same case series co-authored by Dr. Shino Bay Aguilera evaluated a female patient with early traction alopecia. Following three monthly microneedling + PRX⁸ treatments, physician assessment identified visible improvement in hair growth, density, and scalp coverage.
Collagen P.I.N. • 0.5 mm • 3 Monthly Treatments
Refractory Melasma • Fitzpatrick V
In a case report co-authored by Dr. Shino Bay Aguilera, a Fitzpatrick V patient with longstanding melasma underwent four Collagen P.I.N. treatments followed by topical PRX⁸. Physician assessment estimated approximately 50% improvement at final follow-up.
Collagen P.I.N. • 0.7 mm • 4 TreatmentsIndividual results may vary. Hair and melasma results shown are from limited clinical case reports/case series and should not be interpreted as evidence that identical outcomes will occur in other patients.
Clinical context
Provider-led protocols explored beyond traditional facial rejuvenation.
Clinical case work involving PRX⁸ has evaluated its use alongside Collagen P.I.N. microneedling for both nonscarring alopecia and refractory melasma in Fitzpatrick skin type V.
Plant-Based Exosomes for Nonscarring Alopecia
A two-patient case series evaluated androgenetic and traction alopecia using three monthly 0.5-mm Collagen P.I.N. treatments with PRX⁸ during and immediately following microneedling, supplemented by daily topical use between sessions.
Co-authored by Shino Bay Aguilera, DO
Refractory Melasma in Fitzpatrick Skin Type V
A single-patient case report evaluated four treatments performed every two weeks using 0.7-mm Collagen P.I.N. microneedling followed immediately by topical PRX⁸.
Co-authored by Shino Aguilera, DO
These reports represent early clinical evidence. Larger controlled studies are needed to establish reproducibility, efficacy, optimal protocols, and long-term safety.
Key ingredients
The stimulation story behind PRX⁸
A professional blend of Plant Exosomes, Copper Tripeptides, micro-encapsulated retinol, hydration support, and complementary minerals designed for advanced provider-led treatment protocols.
PRX⁸
PRX⁸ Complex™
Turnover + collagen support
PXO
Plant Exosomes
Communication + delivery support
CTP
Copper Tripeptides
Collagen signaling support
ATR
All-Trans Retinol (0.5%)
Micro-encapsulated renewal support
HYD
Sodium Hyaluronate + Glycerin
Hydration + comfort support
MIN
Magnesium Aspartate, Zinc Gluconate + Copper Gluconate
Supportive mineral complex
Best used for
Advanced microneedling protocols where stimulation and continued renewal are part of the treatment strategy.
- Facial rejuvenation and collagen-focused microneedling
- Visible tone, texture, and skin-quality concerns
- Provider-directed pigment protocols
- Scalp microneedling and hair-restoration programs
- Structured continuation between professional treatment sessions
- Protocols designed to reinforce visible results beyond the treatment room
How to use PRX⁸
Professional use with provider-directed continuation.
Integrate PRX⁸ into professional treatment protocols according to the patient, treatment modality, and intended outcome. Continued at-home use may be directed by the treating provider when appropriate.
- Professional use only
- Begin with properly cleansed and prepared skin or scalp
- Apply according to the provider’s established treatment protocol
- May be incorporated into microneedling treatment and immediate post-treatment care
- Provider may direct continued home use when appropriate
- Provide appropriate skincare and photoprotection guidance based on the treatment performed
Clean protocol fit
Made to support modern professional skincare routines.
- Paraben-free
- Dermatologist tested
- Non-comedogenic
- Cruelty-free
- Fragrance-free
- Gluten-free
- Vegan

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