Induction Therapies didn't discover retinol when it became popular. We built formulas around it, developed protocols around it, studied it, and learned how skin adapts to it.
Y.E.S.S.® pairs encapsulated 1% All-Trans Retinol with trichloroacetic acid and hyaluronic acid. The retinol is the ingredient. Keeping it stable, tolerable, and effective beside an acid is the formulation.
Retinol bound to a fatty acid, such as palmitate or acetate. It must be hydrolyzed back to retinol before conversion begins, and retinyl palmitate is only about 55% retinol by weight.
The alcohol form of vitamin A (C₂₀H₃₀O, 286.46 g/mol) and the reference form vitamin A is measured against. Two oxidation steps from the active form, which moderates activity and supports tolerance.
Formed when skin oxidizes retinol. One step from retinoic acid.
Tretinoin. Acts on retinoid receptors directly, needs no conversion, and is prescription-only as a topical drug.
Esters need an extra conversion step and carry less retinol by weight. We formulate with All-Trans Retinol, the reference form of vitamin A.
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Microencapsulation shields retinol from oxygen and light and moderates how much reaches the skin at once. In Pearls of Retinol, the encapsulated retinol is visible as suspended pearls.
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Plant XO pads use 0.5% and 1.0% for home renewal. Pro Plant XO uses 4.0% and 8.0% inside supervised in-office protocols. Different tools, not just different strengths.
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PRX⁸ pairs micro-encapsulated 0.5% retinol with Plant Exosomes, copper tripeptides, and sodium hyaluronate for the recovery window after a procedure.
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Plant XO surrounds its retinol with an antioxidant system (THD ascorbate, tocopherol, ferulic acid) and squalane to support skin resilience through renewal.
View ProductRetinol rarely fails because it doesn't work. It fails because patients stop using it.
All-Trans Retinol is degraded by oxygen, light, heat, trace metals, and acids. Encapsulation surrounds the molecule so it holds up in the jar and on the counter.
Instead of the full dose landing on the skin surface at application, encapsulated retinol releases gradually. Lower peaks, longer contact.
Moderated release means less of the redness and peeling that make patients abandon retinol in the first month.
Skin that adapts to nightly retinol can move, where appropriate, to corrective combinations and eventually to professional treatment.
Stronger skin can tolerate more sophisticated skincare. The provider sets the pace, and many patients stay at maintenance for years.
You prescribe it. Recommend it. Maybe even use it every night. But how well do you actually know retinol?
From the retail shelf to the treatment chair. Select an application.
A slow-release nightly serum patients can sustain for years, starting a few nights a week.
View ProductEncapsulated retinol with TCA and hyaluronic acid for discoloration and uneven texture.
View ProductAt-home retinol peel pads with Plant Exosomes that keep renewal going between appointments.
View Product4.0% and 8.0% pads that promote controlled peeling within a provider-led protocol, with post-care.
View ProductApplied in the treatment room after a procedure, then continued at home through the recovery window.
View ProductWe formulate around two outcomes at once: retinoid activity and skin tolerance.
Retinol carries four conjugated double bonds, all in the trans configuration. UV (absorption peak near 325 nm) and heat can twist them into cis isomers. Pure retinol is pale yellow: the color of these Pro Plant XO pads is the retinol.
Retinol is degraded by oxygen, light, heat, trace metals, and acids. We respond with encapsulation, antioxidant partners, and PM use. Y.E.S.S.® pairs its encapsulated retinol with TCA, one reason encapsulation matters.
Irritation tracks with how much retinol reaches the skin surface at once. PRX⁸ uses micro-encapsulated 0.5% retinol designed to release more slowly.
A 1% retinyl palmitate is only about 0.55% retinol by weight. And Plant XO at 0.5% / 1.0% for home use versus Pro Plant XO at 4.0% / 8.0% in-office are different tools, not just different strengths.
Single-site, open-label pilot at Tennessee Clinical Research Center. 22 women enrolled, ages 41–60, Fitzpatrick II–IV, Glogau II–III; nightly use with IT Cleanse and Block IT SPF30 for 12 weeks; Visia CR imaging. Subject-reported lines, wrinkles, and discoloration improved in 38.1% of subjects; not significant. Dr. Gold is a consultant to Induction Therapies, and the research center was compensated. Read the study (PDF)
Characterization: NanoFCM, commissioned by the manufacturer; PRX⁸ median particle size 66.2 nm, 62% membrane-positive. Case report: Rafael E. Mojica, DO, FAAD, and Shino Aguilera, DO (affiliated with Induction Therapies). 62-year-old patient who had failed hydroquinone and tranexamic acid; 2-month washout; daily sunscreen. Retrospectively estimated scoring; the authors call for controlled studies. Microneedling device claims are outside the scope of this page. Case report (PDF) · NanoFCM report (PDF)
Ordered by where each formula belongs in a retinol strategy.
Years of All-Trans Retinol formulation, under your practice's name. We handle formulation, branding, packaging, and production in our FDA-inspected facility.
