Y.E.S.S.®
Y.E.S.S.®
Description
Y.E.S.S.®
Clinically Tested All-Trans Retinol and TCA Complex
Y.E.S.S.® is a clinically tested nightly renewal serum designed for patients who want visible age support, better texture, and brighter-looking skin from a truly differentiated formula. At the center of the product is a highly effective pairing: 1.0% micro-encapsulated All-Trans Retinol and Trichloroacetic Acid (TCA), combined in one treatment to help improve the look of fine lines, wrinkles, discoloration, dehydration, and uneven texture.
What makes Y.E.S.S. especially compelling is the synergy of the formula. The micro-encapsulated All-Trans Retinol helps support collagen-focused skin renewal with a slower, more controlled release, while TCA helps exfoliate, rebalance discoloration, refine pores, and improve the overall look of skin tone and texture. Rather than acting like a standard retinol serum, Y.E.S.S. delivers a more comprehensive renewal story—one that targets aging skin from multiple visible angles at once.
The formula is also built to support tolerance. Hyaluronic Acid helps deeply hydrate to offset dryness commonly associated with retinoid use, while Shea Butter and Squalane help nourish the barrier, support comfort, and maintain healthier-looking skin through continued nightly use. The result is a high-performance serum that feels advanced, clinically relevant, and meaningfully different from typical retinol products.
Who it’s for
Y.E.S.S. is ideal for:
- Skin aging
- Fine lines and wrinkles
- Uneven texture
- Visible discoloration
- Dehydrated skin
- Loss of radiance
- Pore refinement support
- Nightly renewal routines
What it does
Renews, smooths, hydrates, and helps skin look clearer, firmer, and more youthful.
- Uses 1.0% micro-encapsulated All-Trans Retinol to support visible collagen renewal
- Pairs retinol with TCA to help improve tone, texture, and discoloration
- Helps visibly reduce the appearance of fine lines and wrinkles
- Supports smoother texture and a more refined-looking surface
- Helps improve the look of uneven tone and dullness
- Provides hydration support to offset retinol-associated dryness
- Helps maintain barrier comfort with Shea Butter and Squalane
- Supports a brighter, more polished-looking complexion with continued use
Why it’s different
A true retinol-plus-acid complex, not a standard retinol serum.
Many retinol products rely on a single active story. Y.E.S.S. is more sophisticated. By combining micro-encapsulated All-Trans Retinol with Trichloroacetic Acid, it helps address the visible concerns that often show up together in aging skin: texture, discoloration, dehydration, pore appearance, and loss of overall radiance.
The micro-encapsulation matters here. It helps create a more controlled release of retinol for a better tolerance story, while the supporting hydration system helps offset dryness and irritation. That gives providers and patients a stronger pathway to consistent nightly use without sacrificing the product’s visible performance potential.
Clinical study highlights
Clinically tested for visible improvement and daily tolerability.
- Tested in a 12-week open-label pilot study
- Significant improvement observed in radiance, tone, smoothness, texture, and overall appearance
- Improvement increased with continued use through 12 weeks
- More than half of subjects also showed improvement in elasticity, redness, and dryness-related appearance
- Daily evening use was well tolerated
Key ingredients
The clinical renewal story behind Y.E.S.S.
A high-performance combination of retinol, TCA, hydration, and barrier-supportive ingredients designed to improve aged, uneven, and dehydrated skin with nightly use.
TCA
Trichloroacetic Acid
Discoloration and texture support
ATR
All-Trans Retinol (1.0%)
Controlled-release collagen support
HA
Hyaluronic Acid
Hydration to offset dryness
SB
Shea Butter
Barrier nourishment
SQ
Squalane
Oil balance and irritation support
Best used for
A clinically relevant nightly serum for aging, discoloration, texture, and dehydration.
- Nightly age-support routines
- Fine lines, wrinkles, and texture refinement
- Discoloration and uneven tone concerns
- Dehydrated skin that still needs active renewal
- Patients wanting a more unique retinol treatment story
How to use Y.E.S.S.
Apply at night for steady, visible skin renewal.
Apply to the face, neck, and décolleté at night, or as directed by your skincare provider. For retinol-sensitive users, begin gradually and increase frequency as tolerated until consistent nightly use is established.
- Start with clean, dry skin
- Apply a thin, even layer to face, neck, and décolleté
- Use in the evening only
- Increase gradually if needed based on skin tolerance
- Use sunscreen consistently during daytime routines
Clean protocol fit
Made to support modern professional skincare routines.
- Paraben-free
- Dermatologist tested
- Non-comedogenic
- Cruelty-free
- Fragrance-free
- Gluten-free
- Vegan

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